EUPAHW

Call1

Requests and Offers

Back to list
Shi Yan
Austria
University of Veterinary Medicine Vienna
University
parasitic worms, helminth, vaccine, glyco-enginneering, recombinant antigens
1. Novel Technologies for Prevention, Detection, Assessment and Management of Animal Health and Welfare
My name is Dr. Shi Yan (Orcid: 0000-0003-4949-9140). I am a biochemist and biotechnologist by training. I have been working on free-living and parasitic nematodes for the past 15 years. My research has been focused on the investigation of key enzymes that participate in the glycosylation of nematode proteins, of which many are promising vaccine or drug targets. By engineering the proteins of interest using molecular biological tools, we could achieve a good yield, high solubility and the desired glycan modifications of recombinant proteins. I am very enthusiastic to conduct further glyco-engineering work on helminth antigens, which is a technical trend and is considered to be beneficial to improve the antigenicity of such proteins.
I am interested in teaming up with researchers and vaccine developers, who use modern technology to produce recombinant parasite antigens, regardless of which system you use or favour. The recombinant products can be characterised by me using modern analytical methods such as mass spectrometry and their biological properties, i.e., stimulating cytokine secretion, can be assessed in vitro. Vaccine efficacy trials can be coordinated with veterinary specialists on campus.
The Vetmeduni Vienna (University of Veterinary Medicine Vienna) is one of the oldest vet schools in Europe with over 250 years of history. More information please find on the official webpage (https://www.vetmeduni.ac.at/en/).